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Local anesthetic - Wikipedia
A local anesthetic (LA) is a medication that causes absence of all sensation (including pain) in a specific body part without loss of consciousness, providing local anesthesia, as opposed to a general anesthetic, which eliminates all sensation in the entire body and causes unconsciousness. Local … See more
LAs are of 2 types:
• Clinical LAs:
• Synthetic LAs
Synthetic cocaine-derived LAs differ from cocaine because they have a much lower abuse potential and … See moreLocal anesthetics may be used to prevent and/or treat acute pain, to treat chronic pain, and as a supplement to general anesthesia. See more
All LAs are membrane-stabilizing drugs; they reversibly decrease the rate of depolarization and repolarization of excitable membranes (like nociceptors). Though many other … See more
Local anesthetic solutions for injection typically consist of:
• The local anesthetic agent itself
• A vehicle, which is usually water-based or just sterile water
• Vasoconstrictor possibly (see below) See more
Short Duration of Action and Low Potency
• Benzocaine
• Procaine
• Chloroprocaine
• Cocaine
Medium Duration of … See moreLocalized side effects
Edema of tongue, pharynx and larynx may develop as a side effect of local anesthesia. This … See moreLocal anesthetics can block almost every nerve between the peripheral nerve endings and the central nervous system. The most peripheral technique is topical anesthesia to the … See more
Wikipedia text under CC-BY-SA license Local anesthesia - Wikipedia
Local pain management that uses other techniques than analgesic medication include:
• Transcutaneous electrical nerve stimulation, which has been found to be ineffective for lower back pain , however, it might help with diabetic neuropathy.
• Pulsed radiofrequency, neuromodulation, direct introduction of medication and nerve ablation may be used to target either the tissue structures and organ/systems responsible for persistent nociception or the nociceptors from the str…Wikipedia · Text under CC-BY-SA license- Estimated Reading Time: 5 mins
List of local anesthetics - Wikipedia
This is a list of local anesthetic agents. Not all of these drugs are still used in clinical practice and in research. Some are primarily of historical interest.
- Estimated Reading Time: 2 mins
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Local Anesthetics: Review of Pharmacological …
Local anesthetics interrupt neural conduction by inhibiting the influx of sodium ions through channels or ionophores within neuronal membranes. Normally these channels exist in a resting state, during which sodium ions are denied entry.
Local anesthetics - WikiAnesthesia
Mar 15, 2022 · Local anesthetics are the defining medication class for regional and local anesthesia. They transiently inhibit sensory, motor, and autonomic nerve function depending …
Local anesthetics - WikEM
Local Anesthetics (ester and amide-type). http://www.globalrph.com/local-anesthetics.htm. ↑ Pavlidakey PG et al. Diphenhydramine as an Alternative Local Anesthetic Agent. J Clin …
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Local Anesthesia: Types, Benefits, and Side Effects - WebMD
Oct 2, 2024 · Local anesthesia numbs a part of your body so that your doctor can stitch up a wound or take a biopsy without you feeling any pain. Unlike general anesthesia, where you are …
Local Anesthesia: Uses, Types, Process, Risks, and …
Sep 17, 2018 · Local anesthesia refers to using a drug called an anesthetic to temporarily numb a small area of your body. Your doctor might use a local anesthetic before doing a minor procedure, such as...
Local anaesthesia - NHS
Learn what local anaesthesia is, how it works, and when it's used for various medical procedures. Find out about the possible side effects and precautions of local anaesthetics.
Local anesthesia: Uses, types, side effects, and safety
Jan 17, 2024 · What is local anesthesia, what is it used for, and what are common side effects? Is it safe? Local anesthesia prevents pain during procedures by blocking nerves from transmitting pain...
Anesthetic - Wikipedia
Local anesthetic agents prevent the transmission of nerve impulses without causing unconsciousness. They act by reversibly binding to fast sodium channels from within nerve fibers, thereby preventing sodium from entering the fibres, …
Local Anesthesia: What It Is, Uses, Side Effects & Types
4 days ago · But providers sometimes combine local anesthesia with sedation so you feel relaxed. Some medications containing mild local anesthetics — like cold sore gels — are also available …
Local Anesthetic (LA): a short introduction
Local anesthetics are agents that produce a reversible blockade of neural transmission in autonomic, sensory and motor nerve fibers. Mechanism of action: Reversibly inhibits nerve …
Local anesthetic toxicity - WikiAnesthesia
Sep 12, 2022 · Local anesthetic systemic toxicity (LAST) results from excessive plasma concentrations of local anesthetic drugs. It is a rare but potentially fatal event. It is most often …
Local anesthetic - Wikiwand
A local anesthetic (LA) is a medication that causes absence of all sensation (including pain) in a specific body part without loss of consciousness, providing local anesthesia, as opposed to a …
Local anesthetic - wikidoc
A local anesthetic is a drug that causes reversible local anesthesia and a loss of nociception. When it is used on specific nerve pathways (nerve block), effects such as analgesia (loss of …
Anesthesia - Wikipedia
Local anesthesia is simple infiltration by the clinician directly onto the region of interest (e.g. numbing a tooth for dental work). Peripheral nerve blocks use drugs targeted at peripheral …
Local Anesthetics | Anesthesia Key
May 31, 2016 · Local anesthetics consist of a lipophilic end and a hydrophilic end connected by a hydrocarbon chain. The lipophilic end is an aromatic ring, and the hydrophilic end is a tertiary …
14: Local Anesthetics - Anesthesia Key
May 31, 2016 · 1 What role do local anesthetics play in the practice of anesthesiology? As local anesthetics reversibly block nerve conduction, they are used to provide regional anesthesia for …
Category:Local anesthetics - Wikipedia
Wikimedia Commons has media related to Local anesthetics. The following 83 pages are in this category, out of 83 total. This list may not reflect recent changes.
Local Anesthetic Systemic Toxicity: Symptoms & Treatment
4 days ago · Local anesthetic systemic toxicity causes. The most common cause of LAST is accidental injection of the local anesthetic medication into a blood vessel. Nerve blocks that …
Pharmacology of Local Anaesthetics | SpringerLink
Mar 22, 2025 · The local anaesthetic in the human body is present in two forms: a basic, fat-soluble undissociated form and a dissociated (cationic) water-soluble form. Both forms …
Preanesthetic agent - Wikipedia
Examples of preanesthetic agents are: Acepromazine [1]; atropine [1]; diazepam [1]; Scopolamine; Opioid analgesics, such as morphine, pethidine and buprenorphine.; These drugs are used …
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