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168,903 bpPhage T4 has provided countless contributions to the paradigms of genetics and biochemistry. Its complete genome sequence of 168,903 bp encodes about 300 gene products. T4 biology and its genomic sequence provide the best-understood model for modern functional genomics and proteomics.journals.asm.org/doi/10.1128/mmbr.67.1.86-156.2003Bacteriophage T4 genome - PubMed
Phage T4 has provided countless contributions to the paradigms of genetics and biochemistry. Its complete genome sequence of 168,903 bp encodes about 300 gene products. T4 biology and its genomic sequence provide the best-understood model for modern functional genomics and …
- Author: Eric S. Miller, Elizabeth Kutter, Gisela Mosig, Fumio Arisaka, Takashi Kunisawa, Wolfgang Rüger
- Publish Year: 2003
See results only from pubmed.ncbi.nlm.nih.govBacteriophage T4 Genome …
Functional genome map of bacteriophage T4. The coding capacity of the T4 …
Bacteriophage T4 Head: Str…
Bacteriophage (phage) T4 has served as an extraordinary model to elucidate …
A Restriction Map of the Bac…
We report a detailed restriction map of the bacteriophage T4 genome and the …
Structure, Assembly, and D…
The bacteriophage T4 head is an elongated icosahedron packed with 172 kb of …
Gamma-T4 hybrid bacteriop…
Among 32 lambda-T4 recombinant phages selected for growth on a thymidylate …
The Battle between Bacteri…
The genome of some virulent phages may be modified by harboring a rare base …
Initiation of bacteriophage T…
Bacteriophage T4 initiates DNA replication from specialized structures that form in …
Structure and function of ba…
Bacteriophage T4 is the most well-studied member of Myoviridae, the most …
Bacteriophage T4 Genome - PMC - PubMed Central …
Functional genome map of bacteriophage T4. The coding capacity of the T4 genome is shown for both characterized and hypothetical ORFs. The color scheme (by gene function) is as defined in Table 3. Origins of DNA replication …
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Bacteriophage T4 Head: Structure, Assembly, and …
Bacteriophage (phage) T4 has served as an extraordinary model to elucidate biological structures and mechanisms. Recent discoveries on the T4 head (capsid) structure, portal vertex, and genome packaging add a significant body …
Bacteriophage T4 Genome - Microbiology and Molecular Biology …
Bacteriophage T4 endonucleases II and IV, oppositely affected by dCMP hydroxymethylase activity, have different roles in the degradation and in the RNA polymerase-dependent …
Bacteriophage T4 Head: Structure, Assembly, and Genome …
Feb 14, 2023 · Bacteriophage (phage) T4 has served as an extraordinary model to elucidate biological structures and mechanisms. Recent discoveries on the T4 head (capsid) structure, …
(PDF) Bacteriophage T4 Genome - ResearchGate
Apr 1, 2003 · Functional genome map of bacteriophage T4. The coding capacity of the T4 genome is shown for both characterized and hypothetical ORFs. The color scheme (by gene function) is as defined in...
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Engineering of Bacteriophage T4 Genome Using CRISPR-Cas9
Jun 28, 2017 · We developed a genome editing strategy by codelivering into E. coli a CRISPR-Cas9 plasmid and a donor plasmid containing the desired mutation (s). Single and multiple …
Structure, Assembly, and DNA Packaging …
The bacteriophage T4 head is an elongated icosahedron packed with 172 kb of linear double-stranded DNA and numerous proteins. The capsid is built from three essential proteins: …
Structure and function of bacteriophage T4 - PubMed
Bacteriophage T4 is the most well-studied member of Myoviridae, the most complex family of tailed phages. T4 assembly is divided into three independent pathways: the head, the tail and …
Abstract: Bacteriophage (phage) T4 has served as an extraordinary model to elucidate biological structures and mechanisms. Recent discoveries on the T4 head (capsid) structure, portal …
Bacteriophage T4: Structure, Genetics, and Therapeutic Potential
Oct 10, 2024 · T4’s genome is a treasure trove of regulatory elements that orchestrate the timing of gene expression. These regulatory networks ensure that the viral genes are expressed in a …
A Restriction Map of the Bacteriophage T4 Genome - PMC
We report a detailed restriction map of the bacteriophage T4 genome and the alignment of this map with the genetic map. The sites cut by the enzymes Bgl II, Xho I, Kpn I, Sal I, Pst I, Eco …
CRISPR/Cas9-Mediated Genome Editing of T4 Bacteriophage for …
Oct 29, 2024 · The wild-type T4 phages (T4 WT) are engineered with a lacZa gene through the CRISPR/Cas9 system, generating T4 lacZa phages. After that, the T4 lacZa phages are used …
T4 Bacteriophage: Structure, Function, and Latest Insights
Mar 22, 2025 · The T4 bacteriophage possesses a double-stranded DNA genome of approximately 169 kilobase pairs, encoding over 280 genes. Its genome is packaged with …
T4 Bacteriophage: Structure, Replication, and Research …
Jan 9, 2025 · The T4 bacteriophage’s genetic material is a double-stranded DNA molecule, intricately organized to optimize the infection and replication process. This DNA carries all the …
There are approximately 50 structural proteins that as-semble the virus which is constructed with protein data-bank (PDB) structures and one cryoEM reconstruction from the Electron …
Structural Model of Bacteriophage T4 - ResearchGate
Jan 1, 2021 · In studying bacteriophage T4--one of the basic models of molecular biology for several decades--there has come a Renaissance, and this virus is now actively used as object …
Initiation of bacteriophage T4 DNA replication and replication fork ...
Dec 3, 2010 · Bacteriophage T4 initiates DNA replication from specialized structures that form in its genome. Immediately after infection, RNA-DNA hybrids (R-loops) occur on (at least some) …
Enhancing Amplification Efficiency and Reducing Molecular …
3 days ago · Mapping the interactions of the single-stranded DNA binding protein of bacteriophage T4 (gp32) with DNA lattices at single nucleotide resolution: gp32 monomer …
The change of long tail fibers expanded the host range of a T5 …
5 days ago · Genome sizes were 110, 316 bp for PH204 and 111, 639 bp for SP76, with average GC contents of 39% and 39.9%, respectively. ... Bacteriophage T4 host range is expanded by …
Gamma-T4 hybrid bacteriophage carrying the thymidine kinase …
Among 32 lambda-T4 recombinant phages selected for growth on a thymidylate synthetase-deficient (thyA) host, 2 were shown to carry the T4 thymidine kinase (tk) gene. The lambda …
Bacterial lysis or survival after infection with phage Sf14 depends …
6 days ago · Bacteriophage Sf14 is a Moogle-like myovirus that was isolated during a 2016 shigellosis outbreak in Michigan . Unlike many previously described S. flexneri phages, it can …
The Battle between Bacteria and Bacteriophages: A Conundrum …
The genome of some virulent phages may be modified by harboring a rare base hydroxymethylcytosine (HMC) in place of the base cytosine. This modification enables T4 …
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