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Recent advances in human pluripotent stem cell (hPSC) research have provided us with useful tools to potentially acquire a substantial amount of human McSCs and functional melanocytes …

Sep 11, 2008 · Melanocytes exhibit almost unlimited self-renewal capacity during regenerative processes such as mammalian hair recoloration and zebrafish fin regeneration. Melanoma …

Regeneration of melanocytes in the regenerating zebrafish caudal fin, or following larval melanocyte-specific ablation, or recruitment of new melanocytes during pigment pattern …

This review summarizes the rapidly developing field of epidermal stem cell research, paying particular attention to melanocyte stem cells, their biology and some of the processes that …

Quiescence, maintenance, activation, and proliferation of MelSC are controlled by specific activities in the microenvironment that can influence the differentiation and regeneration of …

Jun 30, 2009 · Melanocyte stem cells offer an advantageous model by which to elucidate molecular basis of stem cell regulation, since genetic alterations affecting melanocyte …

May 22, 2024 · In controlling and coordinating the homeostasis, repair and regeneration of skin tissue, MSCs play a vital role. Decreased numbers or impaired functions of MSCs are closely …

Repigmentation in vitiligo is the process that replaces, in the epidermal basal layer of vitiligo skin, the mature melanocytes that have been killed by cytotoxic T cells specific for melanocyte …

Studies on flatworms now reveal specialized populations of differentiated cells that transiently emerge to coordinate whole body regeneration. The stem cell-centric view of repair processes …

Jun 10, 2011 · Melanocyte stem cells (McSCs) intimately interact with epithelial stem cells (EpSCs) in the hair follicle bulge and secondary hair germ (sHG). Together, they undergo …

Sep 11, 2008 · Melanocytes exhibit almost unlimited self-renewal capacity during regenerative processes such as mammalian hair recoloration and zebrafish fin regeneration. Melanoma …

Mar 22, 2025 · The mammalian hair follicle (HF) serves as a valuable model for studying tissue patterning, regeneration, as well as stem cell biology. In mice, HF morphogenesis begins with …

An improved understanding of the molecular mechanisms that control melanocyte stem cells has the potential to lead to the identification of new drugs that can activate melanocyte stem cells …

Mar 10, 2025 · The team also addressed a long-standing puzzle in the blood stem cell field by showing that the greater regenerative potential of human umbilical cord-derived blood stem …

The team also addressed a long-standing puzzle in the blood stem cell field by showing that the greater regenerative potential of human umbilical cord-derived blood stem cells, compared …

Dec 21, 2015 · Recent advances in human pluripotent stem cell (hPSC) research have provided us with useful tools to potentially acquire a substantial amount of human McSCs and functional …

1 day ago · For decades, scientists have explored whether stem cells could be used to regenerate the retina, but the existence of true retinal stem cells in humans has remained uncertain. In …

Jan 2, 2025 · It was now possible to create autologous cell lines and lines from human leukocyte antigen (HLA) homozygous donors, both serving to reduce or possibly eliminate the need for …

6 days ago · The results are the latest in a series of small human trials testing the potential of iPS cells to regenerate tissue and treat disease. Learning to walk At the one-year follow-up, the …

Dec 21, 2015 · Recent advances in human pluripotent stem cell (hPSC) research have provided us with useful tools to potentially acquire a substantial amount of human McSCs and functional …

3 days ago · Scientists have been looking for a long time for the "switch" that turns regular intestinal cells back into regenerative stem cells, Brumbaugh says. Using animal models, he, …

Stem cells offer new therapeutic avenues for the repair and replacement of damaged tissues and organs owing to their self-renewal and multipotent differentiation capabilities. In this paper, we …

Mar 18, 2025 · Background Hematopoietic stem cell transplantation (HSCT) is a critical treatment for hematologic disorders such as leukemia, lymphoma, and specific immune deficiencies. …

Mar 19, 2025 · Xu, J. et al. Embryonic stem cell-derived mesenchymal stem cells promote colon epithelial integrity and regeneration by elevating circulating IGF-1 in colitis mice. Theranostics …