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Estrogens exert their actions by binding to specific receptors, the estrogen receptors (ERs), which in turn activate transcriptional processes and/or signaling events that result in the control of …

Estrogen receptors (ERs) belong to the family of steroid hormone receptors, which are hormone receptors for sex steroids. Along with androgen receptors (ARs) and progesterone receptors …

In this special issue, “Molecular Pathways of Estrogen Receptor Action”, promising results in understanding the mechanisms underlying ER-mediated effects in various pathophysiological …

Estrogen works through several possible cellular mechanisms to mediate its biological responses as shown in Figure 1. These include two major cellular actions involving the receptors: rapid …

Apr 1, 2005 · Estrogen receptors (ERs) act by regulating transcriptional processes. The classical mechanism of ER action involves estrogen binding to receptors in the nucleus, after which the …

This minireview will discuss the recent progress toward our understanding of the molecular mechanisms of estrogen signaling, focusing on the following four pathways: 1) classical ligand …

Dec 5, 2016 · 17β-Estradiol (E2), as the main circulating estrogen hormone, regulates many tissue and organ functions in physiology. The effects of E2 on cells are mediated by the transcription …

Nov 15, 2024 · In this review we focus on several of the interesting recent discoveries concerning estrogen receptors, on estrogen as a morphogen, and on the molecular mechanisms of anti …

Understanding of E2 physiology and mechanisms of action has undergone a paradigm shift during recent years following the discovery of the second estrogen receptor ERβ.

Estrogen receptor β, in contrast, is found to be critical in mediating E2 signaling in the ovary, prostate, lung, cardiovascular and central nervous systems. Even within a single tissue, the …