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Organizing and summarizing search results for youThe estrogen receptor pathway is crucial in various biological processes. Here are some key points:- Impact on Cancer Cells: Estrogen receptor-positive breast cancer cells can be influenced by compounds like black garlic extract, which inhibits their proliferation and promotes apoptosis.
These findings highlight the importance of estrogen receptors in both normal physiological functions and disease contexts.
PLOShttps://journals.plos.org/plosone/article?id=10.1371/journal.pone.0082436Crosstalk between Wnt/β-Catenin and Estrogen Receptor Signaling ... - PLOSWe find that the activation of estrogen receptor (ER) signaling by estradiol (E2) or exogenously expressed ERα in MPCs synergistically enhances Wnt3A-induced early and late osteoge…PLOShttps://journals.plos.org/plosone/article?id=10.1371/journal.pone.0088961Xenoestrogens Alter Estrogen Receptor (ER) α Intracellular Levels - PLOS17β-estradiol (E2)-dependent estrogen receptor (ER) α intracellular concentration is a well recognized critical step in the pleiotropic effects elicited by E2 in several target tis…PLOShttps://journals.plos.org/plosone/article?id=10.1371/journal.pone.0286454Aged black garlic extract inhibits the growth of estrogen receptor ...In this study, we found that the black garlic extract could inhibit the proliferation, invasion, and metastasis of estrogen receptor-positive breast cancer cells, promote their apo… Estrogen receptor signaling mechanisms - PMC
Estrogen signaling via a linear pathway involving insulin-like growth factor I receptor, matrix metalloproteinases, and epidermal growth factor receptor to activate mitogen-activated protein …
See results only from pmc.ncbi.nlm.nih.govA Basic Review on Estroge…
Therefore, understanding the estrogen pathway is essential for the treatment …
Molecular Pathways of Estro…
The estrogen receptors (ERs) are typical members of the superfamily of nuclear …
Estrogen receptor signaling …
Estrogens exert their actions by binding to specific receptors, the estrogen …
A Basic Review on Estroge…
Therefore, understanding the estrogen pathway is essential for the treatment …
Estrogen Signaling Multiple …
The estrogen receptor β-isoform (ERβ) of the human estrogen receptor modulates …
The many faces of estrogen …
ERα and ERβ are mostly associated with the direct and indirect genomic signaling …
The hypothalamic estrogen r…
The estrogen receptor α (ERα) pathway may play a key role. The aim of the …
Estrogen Receptor Function…
ERα and ERβ are ligand-activated transcription factors of the nuclear …
A Basic Review on Estrogen Receptor Signaling Pathways in …
Therefore, understanding the estrogen pathway is essential for the treatment and new drug development of hormone-dependent cancers. This mini-review summarizes current literature …
Molecular Pathways of Estrogen Receptor Action - PMC
The estrogen receptors (ERs) are typical members of the superfamily of nuclear receptors that includes the receptors that mediate the effects of steroid hormones, thyroid hormones, retinoid …
Estrogen receptor signaling mechanisms - PubMed
Estrogens exert their actions by binding to specific receptors, the estrogen receptors (ERs), which in turn activate transcriptional processes and/or signaling events that result in the control of …
- Author: Nathalie Fuentes, Patricia Silveyra, Patricia Silveyra
- Publish Year: 2019
Estrogen Receptors: How Do They Signal and What …
In this review we focus on several of the interesting recent discoveries concerning estrogen receptors, on estrogen as a morphogen, and on the molecular …
- Author: Nina Heldring, Ashley Pike, Sandra Andersson, Jason Matthews, Guojun Cheng, Johan Hartman, Michel Tu...
- Publish Year: 2007
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Estrogen signaling pathway - Homo sapiens (human)
Estrogen mediates its cellular actions through two signaling pathways classified as "nuclear-initiated steroid signaling" and "membrane-initiated steroid signaling". In the "nuclear" pathway, estrogen binds either ERalpha or ERbeta, which in …
The role of estrogen receptors in intracellular estrogen signaling ...
Jan 1, 2025 · In canonical pathway ESRs can translocate to the nucleus, bind to the target gene promotor with or without estrogen responsive element and regulate transcription, mediating …
Nov 15, 2024 · In this review we focus on several of the interesting recent discoveries concerning estrogen receptors, on estrogen as a morphogen, and on the molecular mechanisms of anti …
The role of estrogen receptors in intracellular estrogen signaling ...
In canonical pathway ESRs can translocate to the nucleus, bind to the target gene promotor with or without estrogen responsive element and regulate transcription, mediating the genomic …
Estrogen receptor signaling mechanisms - ScienceDirect
Jan 1, 2019 · Estrogens exert their actions by binding to specific receptors, the estrogen receptors (ERs), which in turn activate transcriptional processes and/or signaling events that result in the …
A Basic Review on Estrogen Receptor Signaling Pathways in
Apr 6, 2023 · Therefore, understanding the estrogen pathway is essential for the treatment and new drug development of hormone-dependent cancers. This mini-review summarizes current …
Molecular mechanism of estrogen–estrogen receptor signaling
17β-Estradiol (E2), as the main circulating estrogen hormone, regulates many tissue and organ functions in physiology. The effects of E2 on cells are mediated by the transcription factors and …
Molecular classification of hormone receptor-positive /HER2 …
5 days ago · We found that the T-cell receptor (TCR), B-cell receptor (BCR), PD-L1, and HIF-1 signaling pathways were significantly enriched in the ADC + TKI sensitivity group, whereas the …
The many faces of estrogen signaling - PMC - PubMed Central …
Oct 15, 2021 · ERα and ERβ are mostly associated with the direct and indirect genomic signaling pathways that result in target gene expression. Membrane-bound GPER1 is on the other hand …
Connections and Regulation of the Human Estrogen Receptor
May 31, 2002 · Recent genetic, biochemical, and pharmacological dissection of the estrogen signal transduction pathway has led to the identification of numerous proteins and processes …
Estrogen signaling pathway - Cusabio
The actions of estrogen are mediated by the estrogen receptor (ER), a dimeric nuclear protein that binds to DNA and controls gene expression. Estrogen binds to ER to regulate gene …
The hypothalamic estrogen receptor α pathway is involved in high ...
4 days ago · The estrogen receptor α (ERα) pathway may play a key role. The aim of the present study was to confirm the role of adipose/hypothalamic ERα in HIT/MIT-mediated VAT loss, as …
Estrogen receptor α suppresses hepatocellular carcinoma by …
3 days ago · The estrogen receptor is a nuclear receptor family that includes ERα, estrogen receptor β, and membrane estrogen receptor G protein-coupled receptor 30. ERα (also known …
Estrogen Signaling Multiple Pathways to Impact Gene Transcription
The estrogen receptor β-isoform (ERβ) of the human estrogen receptor modulates ERα transcriptional activity and is a key regulator of the cellular response to estrogens and …
Definition of Estrogen Receptor Pathway Critical for Estrogen …
Oct 19, 2006 · We found that estrogen positive feedback to generate the preovulatory gonadotropin surge was normal in estrogen receptor β knockout (ERβ) mutant mice, but …
Role of membrane estrogen receptor alpha on the negative …
4 days ago · Estrogen receptor alpha (ERα) is critical for reproduction, but the relative contributions of its nuclear and membrane signaling are unclear.The present study …
Estrogen Receptor Functions and Pathways at the Vascular …
ERα and ERβ are ligand-activated transcription factors of the nuclear hormone receptor superfamily, while the G protein-coupled estrogen receptor (GPER) mediates estrogenic …
PPAR-gamma agonist pioglitazone improves endometrial …
1 day ago · Serum hormone levels, mature follicle and corpus luteum numbers were increased, indicating improved ovarian function. PIO downregulated the Wnt5/β-catenin signaling …
Estrogen Receptor Functions and Pathways at the Vascular …
Apr 20, 2021 · ERα and ERβ are ligand-activated transcription factors of the nuclear hormone receptor superfamily, while the G protein-coupled estrogen receptor (GPER) mediates …
Definition of estrogen receptor pathway critical for estrogen …
Oct 19, 2006 · We found that estrogen positive feedback to generate the preovulatory gonadotropin surge was normal in estrogen receptor beta knockout (ERbeta) mutant mice, but …
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