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Regeneration of melanocytes in the regenerating zebrafish caudal fin, or following larval melanocyte-specific ablation, or recruitment of new melanocytes during pigment pattern …

This review summarizes the rapidly developing field of epidermal stem cell research, paying particular attention to melanocyte stem cells, their biology and some of the processes that …

May 22, 2024 · In controlling and coordinating the homeostasis, repair and regeneration of skin tissue, MSCs play a vital role. Decreased numbers or impaired functions of MSCs are closely …

Recent advances in human pluripotent stem cell (hPSC) research have provided us with useful tools to potentially acquire a substantial amount of human McSCs and functional melanocytes …

Apr 24, 2019 · Melanocyte stem cells (McSCs) are the undifferentiated melanocytic cells of the mammalian hair follicle (HF) responsible for recurrent generation of a large number of …

MSCs differentiate into mature melanin-producing melanocytes, which confer skin and hair pigmentation and uphold vital skin functions. In controlling and coordinating the homeostasis, …

Sep 8, 2023 · We differentiated human embryonic stem cells (hESCs) that transiently express JMJD3 to pigmented cells. We investigated whether the pigmented cells have melanocytic …

Mar 1, 2013 · Because of their developmental origins, melanocyte stem cells' multipotency and ability to migrate readily to new locations may be innate properties. The multipotent and highly …

4 days ago · A two-step mechanism for stem cell activation during hair regeneration. Cell Stem Cell 4, ... E. K., Granter, S. R. & Fisher, D. E. Mechanisms of hair graying: incomplete …

Regeneration of melanocytes in the regenerating zebrafish caudal fin, or following larval melanocyte-specific ablation, or recruitment of new melanocytes during pigment pattern …

Quiescence, maintenance, activation, and proliferation of MelSC are controlled by specific activities in the microenvironment that can influence the differentiation and regeneration of …

Our analysis emphasizes the active participation of defined molecular pathways that regulate the balance between stemness and differentiation states of melanocytes and keratinocytes: p53 …

Melanocyte stem cells (McSCs) intimately interact with epithelial stem cells (EpSCs) in the hair follicle bulge and secondary hair germ (sHG). Together, they undergo activation and …

An improved understanding of the molecular mechanisms that control melanocyte stem cells has the potential to lead to the identification of new drugs that can activate melanocyte stem cells …

5 days ago · The intestinal epithelium continuously self-renews, with cells generated in the proliferative crypt zone migrating upward, differentiating, and being shed from the villus tips …

Feb 1, 2009 · Regeneration of melanocytes in the regenerating zebrafish caudal fin, or following larval melanocyte-specific ablation, or recruitment of new melanocytes during pigment pattern …

Jun 30, 2009 · Melanocyte stem cells offer an advantageous model by which to elucidate molecular basis of stem cell regulation, since genetic alterations affecting melanocyte …

Mar 14, 2025 · Stem cells play a vital role in skin regeneration, as they have the ability to differentiate into different types of skin cells, including keratinocytes, melanocytes, and …

May 22, 2024 · In controlling and coordinating the homeostasis, repair and regeneration of skin tissue, MSCs play a vital role. Decreased numbers or impaired functions of MSCs are closely …

Feb 25, 2025 · The epidermis develops from the ectoderm, forming specialized cells like keratinocytes, melanocytes, and Merkel cells. The dermis arises from the mesoderm, giving …

Dec 21, 2015 · Recent advances in human pluripotent stem cell (hPSC) research have provided us with useful tools to potentially acquire a substantial amount of human McSCs and functional …

Affiliations 1 Department of Orthopaedic Surgery, UC Davis Health, Sacramento, CA 95817, USA; Institute for Stem Cell Biology and Regenerative Medicine, Stanford University School of …