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Organizing and summarizing search results for youViruses that use reverse transcriptase include:- Human immunodeficiency virus (HIV), which causes acquired immunodeficiency syndrome (AIDS)
- Hepatitis B virus (HBV), which causes a potentially life-threatening liver infection
- Human T-cell lymphotropic virus I (HTLV-I), which causes leukemia
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Reverse transcriptase - Wikipedia
A reverse transcriptase (RT) is an enzyme used to convert RNA genome to DNA, a process termed reverse transcription. Reverse transcriptases are used by viruses such as HIV, COVID-19, and hepatitis B to replicate their genomes, by retrotransposon mobile genetic elements to proliferate within the … See more
Reverse transcriptases were discovered by Howard Temin at the University of Wisconsin–Madison in Rous sarcoma virions and independently isolated by David Baltimore in … See more
The enzymes are encoded and used by viruses that use reverse transcription as a step in the process of replication. Reverse-transcribing RNA viruses, such as retroviruses, … See more
There are three different replication systems during the life cycle of a retrovirus. The first process is the reverse transcriptase synthesis of viral DNA from viral RNA, which then forms newly made complementary DNA strands. The second replication process … See more
Self-replicating stretches of eukaryotic genomes known as retrotransposons utilize reverse transcriptase to move from one position in the genome to another via an RNA … See more
The reverse transcriptase employs a "right hand" structure similar to that found in other viral nucleic acid polymerases. In addition to the … See more
Wikipedia text under CC-BY-SA license Overview of Reverse Transcription - Retroviruses - NCBI Bookshelf
Reverse transcription of the viral RNA genome generates a linear DNA duplex. The positions of the R, U5, and U3 regions, the polypurine tract (PPT), and the primer-binding site (PBS) are …
- Author: John M Coffin, Stephen H Hughes, Harold E Varmus
- Published: 1997
- Publish Year: 1997
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Keeping up with virus taxonomy: reverse-transcribing viruses
Dec 14, 2022 · Some viruses use reverse transcription to replicate and then integrate their own genetic information into their host’s genome. The ‘retro’ in Retroviridae refers to reversing the …
Reverse transcriptase | Enzyme Function & Applications | Britannica
- reverse transcriptase, an enzyme encoded from the genetic material of retroviruses that catalyz…
Retroviruses consist of an RNA genome contained within a protein shell that is enclosed in a lipid envelope. The retrovirus genome is typically made up of three genes: the group-specific antigen gene (gag), the polymerase gene (pol), and the envelope gene (env). The pol gene encodes th…
- reverse transcriptase, an enzyme encoded from the genetic material of retroviruses that catalyz…
Viral reverse transcriptases - PubMed
Apr 15, 2017 · In this review, we summarize current knowledge on reverse transcription in the five virus families and discuss available biochemical and structural information on RTs, including …
- Author: Luis Menéndez-Arias, Alba Sebastián-Martín, Mar Álvarez
- Publish Year: 2017
Reverse Transcriptase: Mechanisms, Structure, and Inhibition
Jan 9, 2025 · Reverse transcriptase is an enzyme that converts RNA into DNA, a process essential for the replication of certain viruses, including retroviruses like HIV. Its significance …
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Reverse Transcription of Retroviruses and LTR …
In retroviruses and LTR retrotransposons, reverse transcription is the conversion of a single-stranded RNA (ssRNA) copy of the genome into a double-stranded DNA (dsDNA). To avoid the loss of genetic information, the dsDNA copy is …
Diversity of reverse-transcriptase-containing viruses through …
Jan 1, 2025 · Viruses that require RT to replicate their genetic material include pathogens and carcinogens in plants, animals, and humans. Examples include the human immunodeficiency …
What is a Reverse Transcriptase? (with pictures)
May 21, 2024 · Reverse transcriptase is a type of enzyme found in a class of viruses called retroviruses, which include HIV, the Hepatitis B virus and some cancer-causing viruses.
Reverse Transcription in Viral Replication: Mechanism and Impact
Oct 10, 2024 · Reverse transcription is a key process in viral replication, especially for retroviruses like HIV. This mechanism allows these viruses to convert their RNA genomes into DNA, …
Reverse Transcriptase and the Generation of Retroviral DNA
Reverse transcription—the reverse or “retro” flow of genetic information from RNA to DNA—is a hallmark of the retroviral replication cycle. The term “retroviruses” has now largely supplanted …
Reverse Transcribing Virus - an overview | ScienceDirect Topics
Reverse-transcribing viruses include important human pathogens, such as the human immunodeficiency viruses type 1 and type 2 (HIV-1 and HIV-2, respectively) and the hepatitis …
Ortervirales: New Virus Order Unifying Five Families of Reverse ...
May 29, 2018 · Reverse-transcribing viruses include prominent human pathogens, such as human immunodeficiency viruses 1 and 2 (HIV-1/2) and hepatitis B virus, as well as plant pathogens …
Which viruses use reverse transcriptase? - AAT Bioquest
Mar 22, 2022 · Several retroviruses use reverse transcriptase to replicate their genomes, which is central to their infectious nature. Some of the more common viruses that use reverse …
Analyzing diversity of reverse-transcriptase-containing viruses …
Jan 10, 2025 · Viral reverse transcriptase (RT) plays a critical role in replication (e.g., retroviruses, that reverse transcribe RNA templates into complementary DNA) and genome mutations (e.g.,...
Animal Viruses: Reverse-Transcribing Virus Synthesis ... - Pearson
Reverse transcribing viruses, particularly retroviruses, utilize the enzyme reverse transcriptase to convert their single-stranded RNA genome into double-stranded DNA.
Reverse Transcribing Virus - an overview | ScienceDirect Topics
Group VII viruses are double-stranded DNA viruses that can integrate their DNA into the host genome, using a reverse transcriptase enzyme. The reverse transcriptase enzyme acts upon …
Reverse Transcriptase Fidelity in Viral Evolution
Oct 20, 2024 · Reverse transcriptase is a pivotal enzyme in the life cycle of retroviruses, such as HIV. Its primary function is to transcribe RNA into DNA, which can then integrate into the host …
Backsplicing of the HIV-1 transcript generates multiple circRNAs …
17 hours ago · In addition, the reverse transcription step allows the reverse transcriptase to begin a rolling circle amplification that generates single-stranded cDNAs formed by a long chain of …
Identification of a novel small-molecule inhibitor of the HIV-1 …
Mar 7, 2025 · Analysis of viruses harboring drug-resistance-associated mutations showed that BPPT was potent against G190A (C or S) mutations in reverse transcriptase (RTase), …
Health Alert Network (HAN) - 00523 | Dengue Virus Infections in …
Mar 18, 2025 · Spring and summer travel coincide with the peak season for dengue in many countries, increasing the risk of both travel-associated and locally acquired cases in the United …
Viral reverse transcriptases - ScienceDirect
Apr 15, 2017 · Viral reverse transcriptases (RTs) have DNA polymerase and RNase H activities. Structural, biochemical and enzymological properties of retroviral RTs are discussed. …
Canonical and non-canonical functions of the non-coding RNA …
Mar 1, 2025 · The telomerase complex consists of a protein component (TERT), which has reverse transcriptase activity, and an RNA component (TERC), which serves as a template for …
Reverse Transcribing Virus - an overview | ScienceDirect Topics
Reverse-transcribing viruses, which synthesize a copy of genomic DNA from an RNA template, are widespread in animals, plants, algae, and fungi.
Reverse genetics system enhances vaccine development for …
2 days ago · The synthetic genomics-based reverse genetics system developed for ASFV can be applied to other viruses with noninfectious genomes, offering significant potential for research …
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